hrp0086p2-p868 | Syndromes: Mechanisms and Management P2 | ESPE2016

Pubertal Development and Final Height in Some Rare Genetic Diseases

Mazzanti Laura , Casto Celeste , Tamburrino Federica , Perri Annamaria , Guidetti Monica , Emanuela Scarano

Background: Pubertal growth, age of puberty onset and pubertal spurt duration are correlated to final height (FH). Few data are available in subjects with rare genetic syndromes.Objective and hypotheses: To evaluate pubertal pattern and its influence on FH in subjects with different genetic syndromes including the effect of GH-therapy for GH deficiency (GHD) and GnRH analogs for precocious puberty (PP).Method: We studied for growth...